NFL

2021 NFL Week 1 odds, lines, more

Aaron Rodgers Week 1 odds NFL
Aaron Rodgers and the Packers meet the Saints in Week 1.
Jeff Hanisch-USA TODAY Sports

Sunday provides the sports gambler with its first big day of the fall as Week 1 of the NFL season kicks off — and the picks already aren’t easy.

The early games feature a big AFC matchup between the Pittsburgh Steelers and the Buffalo Bills — who made it to the AFC Championship Game last season.

At the opposite end of the standings, the Houston Texans and Jacksonville Jaguars meet in a battle of which team will be the worst in the NFL. The football will be bad and those brave enough to pick it might be pulling their hair out.

The Cincinnati Bengals get Joe Burrow back, but can he make a big opening claim against a Minnesota Vikings team that is an afterthought in the NFC North?

What about two 4:25 matchups that pit some of the best in their respective conferences against each other?

In the NFC, Aaron Rodgers and the Green Bay Packers are a pick to get to the title game this year. But the New Orleans Saints will be keen on proving that there is life after Drew Brees.

In the AFC, the two-time defending conference champion Kansas City Chiefs host a Cleveland Browns side hungry to show they belong in the list of elite sides in the NFL.

Here’s what’s on tap this Sunday, with odds courtesy of DraftKings.

 

New York Jets at Carolina Panthers (-4), 1 p.m. ET

  • Total Points Over/Under: 44 (-110)
  • Jets Moneyline: +190
  • Panthers Moneyline: -235

Pittsburgh Steelers at Buffalo Bills (-6.5), 1 p.m.

  • Total Points Over/Under: 48.5 (-110)
  • Steelers Moneyline: +250
  • Panthers Moneyline: -320

San Francisco 49ers (-7.5) at Detroit Lions, 1 p.m.

  • Total Points Over/Under: 44.5 (-110)
  • 49ers Moneyline: -365
  • Lions Moneyline: +280

Jacksonville Jaguars (-3) at Houston Texans, 1 p.m.

  • Total Points Over/Under: 45 (-110)
  • Jaguars Moneyline: -180
  • Panthers Moneyline: +155

Seattle Seahawks (-2.5) at Indianapolis Colts, 1 p.m.

  • Total Points Over/Under: 50 (-110)
  • Seahawks Moneyline: -145
  • Colts Moneyline: +125

Arizona Cardinals at Tennessee Titans (-3), 1 p.m.

  • Total Points Over/Under: 52.5 (-110)
  • Cardinals Moneyline: +140
  • Titans Moneyline: -160

LA Chargers at Washington Football Team (-1), 1 p.m.

  • Total Points Over/Under: 44 (-110)
  • Chargers Moneyline: +100
  • WFT Moneyline: -120

Minnesota Vikings (-3) at Cincinnati Bengals, 1 p.m.

  • Total Points Over: 47.5 (-105)
  • Total Points Under: 47.5 (-115)
  • Vikings Moneyline: -180
  • Bengals Moneyline: +155

Philadelphia Eagles at Atlanta Falcons (-3), 1 p.m.

  • Total Points Over/Under: 49 (-110)
  • Eagles Moneyline: +150
  • Falcons Moneyline: -170

Miami Dolphins at New England Patriots (-3), 4:25 p.m.

  • Total Points Over: 43.5 (-115)
  • Total Points Under: 43.5 (-105)
  • Dolphins Moneyline: +155
  • Patriots Moneyline: -180

Cleveland Browns at Kansas City Chiefs (-5.5), 4:25 p.m.

  • Total Points Over/Under: 54.5 (-110)
  • Browns Moneyline: +220
  • Chiefs Moneyline: -275

Green Bay Packers (-3.5) at New Orleans Saints, 4:25 p.m.

  • Total Points Over/Under: 49 (-110)
  • Packers Moneyline: -200
  • Saints Moneyline: +170

Denver Broncos (-3) at New York Giants, 4:25 p.m.

  • Total Points Over/Under: 42 (-110)
  • Broncos Moneyline: -160
  • Panthers Moneyline: +140

Chicago Bears at Los Angeles Rams (-7.5), 8:20 p.m.

  • Total Points Over/Under: 46.5 (-110)
  • Bears Moneyline: +320
  • Rams Moneyline: -425

More from our Sister Sites